Saturday, March 26, 2011

Pralatrexate




In the US, Pralatrexate (pralatrexate systemic) is a member of the drug class antimetabolites and is used to treat Lymphoma and Non-Hodgkin's Lymphoma.

US matches:

  • Pralatrexate

  • Pralatrexate Intravenous

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01BA05

CAS registry number (Chemical Abstracts Service)

0146464-95-1

Chemical Formula

C23-H23-N7-O5

Molecular Weight

477

Therapeutic Category

Antineoplastic agent

Chemical Names

N-(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic acid (IUPAC)

N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid (WHO)

(2S)-2-[[4-[(1RS)-1-[(2,4-Diaminopteridin-6-yl)methyl]but-3-ynyl]benzoyl]amino]pentanedioic acid (USAN)

10-Propargyl-10-deazaaminopterin

L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butynyl]benzoyl]- (USAN)

Foreign Names

  • Pralatrexatum (Latin)
  • Pralatrexat (German)
  • Pralatrexate (French)
  • Pralatrexato (Spanish)

Generic Names

  • Pralatrexate (OS: USAN)
  • PDX (IS)
  • UNIIA8Q8I19Q20 (IS)

Brand Name

  • Folotyn
    Allos, United States

International Drug Name Search

Glossary

IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

No comments:

Post a Comment